One example of badly missing the big-picture as limited by an atheistic worldview, is to not recognize and factor-in the need for agency to overcome the difficulties in terms of directionally targeted trajectories and prior fitness, that the beginning Hot Big Bang is an explosion.
The fundamental question is not just how does something come out of nothing, but more precisely and profoundly how does something explode out of nothing.
The more knowledgeable and informed question today is how does matter and energy explode out of nothing previously being non-material into physically existent matter and energy.
If our materialistic, agency-excluding worldview requires that self-assembling matter and energy produced the orderliness and intelligibility we observe today in the natural world, how does non-existent matter and energy explode into existing matter and energy at the beginning of the physical universe?
Explosions do not create intelligible order, but instead create chaotic disorder.
We only see order coming out of the Big Bang by looking backwards in hindsight from the vantage point of the perfected order we observe today in the natural world.
I live one street away from the Pacific Ocean in Southern California. Today I am enjoying a clear blue sky, a moderate summer temperature, and a cooling, slight sea breeze.
It is easy for me to take this for granted, having never lived farther than a mile from the beaches in Southern California.
But how many factors must align and be properly sequenced to go from a massive explosion at the Big Bang origin of the universe, to a post-card perfect day along the beach in Southern California?
Science correctly prides itself in saying that it questions and examines everything analytically without prejudice, that it digs deeper than surface appearances, and that it bases its conclusions and axioms on empirical, fact-based evidences.
But the atheism in scientific materialism cannot crossover into contemplating the intelligent designing agency that is required to span the enormous gulf of 13.7 billion years from a beginning Hot Big Bang explosion, by definition being a chaotic event, to arrive at the pleasantness of a clear sunny day along a beach in Southern California.
The number, coordination, and integration of the factors that must be fine-tuned to an inconceivable fit and function outcome of a beautiful sunny sky and pleasant weather at the beach, corresponding to our ability to appreciate this, defies any plausible explanation that leaves God out of the process.
From our current viewpoint looking backwards in time it is easy to take for granted, that of course order arose out of the Big Bang explosion 13.7-billion years ago, because today we observe orderliness actualized in the natural world, that otherwise should be entirely counterintuitive originating out of a massive explosion.
From the time of the Big Bang looking forward, to arrive at the orderliness and intelligibility of the natural world today is asking too much of a random, undirected, accidental, and chance-based, purely materialistic process.
A massive explosion in a book publishing, printing press factory will not generate a dictionary.
A tornado going through a junkyard will not assemble a 747 commercial jetliner.
Italian spaghetti sauce will not make itself.
The old example that 100 monkeys sitting at typewriters randomly banging on the keys for years would eventually by chance alone produce a Shakespeare play, is a bad analogy because 100 monkeys are not the same thing as starting from scratch with absolutely nothing.
Monkeys have the physical body-parts and dexterity to perform random typing, and typewriters are highly engineered and sophisticated instruments for communication.
Time plus chance here is invalid even if successful because the experiment is rigged upfront to propel forward in a certain direction having the built-in means to communicate information.
100 monkeys in a group all talking for a trillion years cannot possibly produce a Shakespeare play because spoken monkey-talk cannot reach the level of information understandable by humans that a typewriter might possibly generate (unless humans devise a way to translate monkey-talk into English).
What should be an obvious fallacy in this analogy to monkeys by sheer chance typing Shakespeare is that we are starting with things that are already extremely complex.
How difficult would it be to create a monkey from scratch capable of being trained to hit typewriter keys?
The typewriter, that a monkey would produce a Shakespeare play on, is an ingeniously complex invention.
This is a fundamental point that needs more attention in the evolution/creation debate that starting from absolutely nothing is not the same thing as progressive development from the simple to the complex.
This is especially true when the simple is not simple at all.
This argument imagining a pathway through time and chance for Darwinian evolution starts by assuming as a given the existence of complex, highly specified, and coherently integrated entities like monkeys and typewriters.
The real question is how to create a Shakespeare play starting with absolutely nothing.
Chance cannot work with nothing.
The concept of the Big Bang origin of the universe is that matter and energy materially arose out of nothing previously material…no monkeys and no typewriters in existence yet.
The concept of the origin of life must start with the reality that DNA and the molecular nanotechnology inside the first living bacteria cell arose out of zero DNA, and no life previously existing on earth.
In our normal experience, explosions do not produce the ordered complexity of coordinated things to the point of being discernable as such, to human investigation through science, like our universe amazingly is.
But equally telling, explosions do not occur out of nothing.
The late scientist Stephen Hawking can brilliantly investigate the origin of the universe through quantum mechanics, looking backwards through an intelligibly ordered, present-day reality.
This is all well and good, and scientists will continue this investigation.
But the narrow focus of the atheism of scientific materialism precludes the fuller picture that would include the obvious question once we see it, of how a massive explosion at the beginning of the universe could over billions of years arrive at an end-point outcome in this 21st century of cognitive, thinking human scientists.
These scientists explore the physically material universe, exploiting with great success this feature of orderliness and intelligibility, arising out of the chaotic disorder of a massive explosion.
Another clear example of atheism blindly sweeping the obvious under the rug, once we see it, is the idea that extra-large stars are needed to condense in size and implode through gravity to produce the exceptionally high heat to make carbon and oxygen, just before exploding to spread these critical elements throughout the cosmos that are essential to enable complex life like ourselves to exist.
The chemical bonding properties of the carbon atom are critical to form the numerous compounds that enable living organisms to exist, yet again a massive explosion of giant stars is required to translate over billions of years this physically material reality into living organisms on earth.
The Big Bang creation of the universe is dated to 13.7-billion years ago, and the first appearance of life on earth is dated to around 3.8-billion years ago.
Doing the math, this equates to a gap of time of nearly 10 billion years from the first existence of the material universe to the beginning of life on earth.
What quality of targeted foresight, absent intelligent designing agency, would be capable of spanning this period of time to connect-the-dots beginning with carbon and oxygen created within exploding supernova stars, to arrive at exquisite end-points of function in the ten-million different species living on earth today exhibiting unique architectural body-plans and lifestyle habits?
The common layman on the street would and does say as the majority opinion that these directionally targeted outcomes of complex, specified, and coherently integrated living organisms could not come about through random and undirected processes commencing with giant, supernova stars exploding 13-billion years ago.
I can easily recognize in this 21st century through the most general understanding of the various parts of my body, through a non-technical introspection of how precisely everything internally works, that I am vastly too complex to be the product of a mindless, blind, accidental, indifferent to outcomes, trial-and-error, and undirected process.
Ask most people the same thing, and given a moment of reflection would agree that we are too complex and too highly specified in terms of function to be the product of a solely matter and energy universe.
As stated in the introduction in this book, the more we learn about the phenomena in the natural world, the weaker becomes the argument for naturalistic materialism.
It is the philosophical element of atheism within scientific materialism that generates the outdated question: “Is there empirical evidence for the existence of God?”
The correct answer is that of course there is no physically material evidence for the existence of the God of the Bible, because God is a non-material, Spirit-Being…but this is not the end of the story.
The difficulty of assembling all of the various parts in the right amounts to create another duplicate planet Earth-2, again highlights the impracticality of physically material creatures like ourselves marshaling the required knowledge and practical means to put together a functional, life-sustaining planet.
The difficulty of building a planet from scratch highlights the inescapable reality that a transcendent, non-material, Spirit-Being of unimaginable capacity would be needed to create our planet earth, unencumbered by the practical limitations of physical existence.
Provisional conclusions, that are abstract concepts attached to scientific research programs, can no more exclude divinely intelligent agency than they can support materialistic atheism as the only worldview acceptable to pure science.
The inference to the best explanation today has only one option.
The creator of this universe has to be a non-material, Spirit-Being possessing the wherewithal to produce a physically material universe, massive sized galaxies, and exquisitely magnificent planets like our earth.
This is an excerpt from my book Pondering Our World: Christian Essays on Science and Faith.
 See the discussion of starting with truly nothing in The Science & Faith Podcast – James Tour & William Dembski: Information Theory, on the Internet, May 3, 2021 on DrJamesTour.